•  

DNA Sequencing versus Standard Prenatal Aneuploidy Screening (Aug 2014)

Title:
DNA Sequencing versus Standard Prenatal Aneuploidy Screening
Journal:
N Engl J Med 2014; 371:577-578, August 7, 2014
Author(s):
Can Liao, M.D., Xu Zhengfeng, M.D., Kang Zhang, M.D. Ph.D.
 

 

Short description:
Bianchi et al. (Feb. 27 issue)1 described noninvasive diagnosis of fetal aneuploidy from cell-free DNA (cfDNA) in maternal plasma with the use of an Illumina HiSeq massively parallel sequencing platform and compared this method with standard prenatal aneuploidy screening. They concluded that prenatal screening by assay of cfDNA had significantly lower false positive rates and higher positive predictive values for detection of trisomies 21 and 18 than did standard screening.
Link to the journal
 

 

Abstract taken from PubMed

Background:
Methods:
Results:
Conclusions:
Link to the paper on PubMed:
Comment in:
 




IVF-Worldwide.com endeavors to ensure that the information in this article is accurate,reliable and up to date. However, the information is provided "as is" without warranty of any kind. IVF-Worldwide does not accept any responsibility or liability for the accuracy,content, completeness, legality, or reliability of the information contained in this article.
IVF-Worldwide.com is not responsible for the content of other websites linked to or referenced from this website. The website does not endorse the information, content,presentation or accuracy of such other websites and does not make any warranty,express or implied, regarding them.