- Title:
- Fertility management in the PCOS population: results of a web-based survey at IVF-worldwide.com
- Journal:
- Journal of Assisted Reproduction and Genetics September 2013, Volume 30, Issue 9, pp 1169-1174
- Author(s):
- Brezina PR1, Mensah V, Balen A, Leong M, Weissman A, Zhao Y, Shoham Z.
- Author(s) affiliation:
- 1Reproductive Genetics, Fertility Associates of Memphis, 80 Humpreys Center, Suite 307, Memphis, TN, 38120-2363, USA, This email address is being protected from spambots. You need JavaScript enabled to view it..
- Short description:
- Link to the journal
Abstract taken from PubMed
- Background:
- To identify the leading treatment strategies for infertile women with PCOS on an international scale.
- Methods:
- A retrospective evaluation using the results of a web-based survey, (IVF-Worldwide (www.IVF-worldwide.com), posted from 1 to 30 September 2010 was performed. Binomial confidence intervals for proportions were calculated by the modified Wald method with significance defined as P < 0.05 using a DataStar software package (DataStar, Waltham, MA, USA). Incomplete surveys were excluded from the analysis.
- Results:
- The results from 262 centers in 68 nations were obtained. Clomiphene citrate was the clear first choice, 68 %, for PCOS treatment in the respondent group. Eighty-eight percent of respondents utilized ultrasound follicular monitoring when conducting ovulation induction with oral medications. A significant (p < 0.05) proportion of respondents (66 %) did use some BMI cutoff beyond which IVF treatment was not offered. The preferred IVF protocols for PCOS patients were gonadotropin releasing hormone (GnRH) antagonist, 46 %, and GnRH agonist, 51 %. There was heterogeneity of responses observed regarding the management of a patient at very high risk of OHSS.
- Conclusions:
- While some advances, such as the use of GnRH antagonist regimen in IVF cycles, were relatively underutilized, the survey gives an unfiltered snapshot at the practice patterns of a large number of clinics. Results from this survey may be used by researchers and professional organizations to improve the clinical care of PCOS women suffering with infertility.
- Link to the paper on PubMed
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